Psychoses are severe mental health conditions in which the perception of reality is temporarily or persistently altered. Affected individuals may have difficulty distinguishing between internal experiences and external reality.

Schizophrenia is one of the most well-known forms of psychotic disorders. It typically follows an episodic course, with acute psychotic phases as well as more stable intervals.

Importantly, psychoses are treatable. Early diagnosis and therapy significantly improve the prognosis.

Symptoms

Symptoms are often divided into positive and negative symptoms:

Positive symptoms (added experiences):

  • Delusions (e.g., persecutory or referential delusions)

  • Hallucinations (e.g., hearing voices)

  • Formal thought disorders

  • Disorganized behavior

Negative symptoms (reduced functions):

  • Lack of drive

  • Social withdrawal

  • Reduced emotional expression

  • Poverty of speech

In addition, concentration and memory problems may occur.

Types

  • Schizophrenia

  • Schizoaffective disorder

  • Acute and transient psychotic disorder

  • Delusional disorder

  • Substance-induced psychosis

Accurate differentiation is essential for treatment planning.

Causes

The development of psychotic disorders is multifactorial:

  • Genetic predisposition

  • Neurobiological changes (e.g., dopamine dysregulation)

  • Psychosocial stress factors

  • Substance use (e.g., cannabis)

  • Stress and sleep deprivation

Usually, several factors interact in combination.